ALK anticorps (AA 636-666)

N° du produit ABIN3029939

Détail du produit anti-ALK anticorps

Antigène: ALK (Anaplastic Lymphoma Receptor tyrosine Kinase (ALK))

Épitope: AA 636-666

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALK est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Purified

Immunogène: A portion of amino acids 636-666 from the human protein was used as the immunogen for this ALK antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the ALK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the ALK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur ALK

Antigène: ALK (Anaplastic Lymphoma Receptor tyrosine Kinase (ALK))

Autre désignation: ALK (ALK Produits)

Synonymes: anticorps Tcrz, anticorps CD246, anticorps NBLST3, anticorps ALK, anticorps anaplastic lymphoma kinase, anticorps anaplastic lymphoma receptor tyrosine kinase, anticorps ALK receptor tyrosine kinase, anticorps Alk, anticorps ALK

Sujet: Anaplastic lymphoma kinase, a member of the insulin receptor subfamily of Tyr protein kinases, is an orphan receptor. It appears to play an important role in the normal development and function of the nervous system. This Type I membrane protein is expressed in brain and CNS and in the small intestine and testis, but not in normal lymphoid cells. A form of non-Hodgkin's lymphoma is characterized by a chromosomal translocation t(2,5)(p23,q35) that involves NPM1 and ALK. The protein contains 1 LDL-receptor class A domain and 2 putative MAM domains.

UniProt: Q9UM73

Pathways: Signalisation RTK