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AXIN2 anticorps (AA 816-843)

AXIN2 Reactivité: Humain WB, IHC, ELISA, FACS Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3030089
  • Antigène Voir toutes AXIN2 Anticorps
    AXIN2 (Axin 2 (AXIN2))
    Épitope
    • 15
    • 13
    • 11
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 816-843
    Reactivité
    • 70
    • 53
    • 40
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 83
    • 2
    Lapin
    Clonalité
    • 74
    • 11
    Polyclonal
    Conjugué
    • 24
    • 8
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp AXIN2 est non-conjugé
    Application
    • 62
    • 37
    • 29
    • 13
    • 13
    • 13
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
    Réactivité croisée (Details)
    Expected species reactivity: Mouse, Rat
    Purification
    Antigen affinity purified
    Immunogène
    A portion of amino acids 816-843 from the human protein was used as the immunogen for this AXIN2 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product AXIN2 Anticorps primaire
  • Indications d'application
    Titration of the AXIN2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot the AXIN2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Antigène
    AXIN2 (Axin 2 (AXIN2))
    Autre désignation
    AXIN2 (AXIN2 Produits)
    Synonymes
    anticorps AXIL, anticorps ODCRCS, anticorps axil, anticorps wu:fb37c08, anticorps zgc:111942, anticorps axin-2, anticorps xarp, anticorps MGC81576, anticorps arp-A, anticorps axin2, anticorps Axi1, anticorps Axil, anticorps Conductin, anticorps axin 2, anticorps axin 2 (conductin, axil), anticorps axin 2 (conductin, axil) S homeolog, anticorps AXIN2, anticorps axin2, anticorps axin2.S, anticorps Axin2
    Sujet
    The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair.
    UniProt
    Q9Y2T1
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
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