BNIP3
Reactivité: Humain
WB, IF, ICC
Hôte: Lapin
Polyclonal
Biotin
Indications d'application
Titration of the BNIP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:50-1:100,IHC (Paraffin): 1:50-1:100
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Aliquot the BNIP3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Antigène
BNIP3
(BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))
anticorps NIP3, anticorps Nip3, anticorps BCL2 interacting protein 3, anticorps BCL2/adenovirus E1B interacting protein 3, anticorps BNIP3, anticorps Bnip3
Sujet
NIP3 is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. NIP3 contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein is known to induce apoptosis, even in the presence of BCL2.