C4B anticorps (AA 655-684)

N° du produit ABIN3030240

Détail du produit anti-C4B anticorps

Antigène: C4B (C4b) (Complement Component C4b (C4b))

Épitope: AA 655-684

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C4B est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): Expected species reactivity: Human

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 655-684 from the human protein was used as the immunogen for this C4B antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the C4B antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the C4B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur C4B

Antigène: C4B (C4b) (Complement Component C4b (C4b))

Autre désignation: C4B (Complement 4b) (C4b Produits)

Synonymes: anticorps C4B1, anticorps C4B12, anticorps C4B2, anticorps C4B3, anticorps C4B5, anticorps C4BD, anticorps C4B_2, anticorps C4F, anticorps CH, anticorps CO4, anticorps CPAMD3, anticorps C4, anticorps C4A2, anticorps C4A3, anticorps C4A4, anticorps C4A6, anticorps C4AD, anticorps C4S, anticorps CPAMD2, anticorps RG, anticorps wu:fi14a03, anticorps C4B, anticorps DKFZP469I0332, anticorps Slp, anticorps Ss, anticorps C4-2, anticorps C4l, anticorps complement C4B (Chido blood group), anticorps complement C4A (Rodgers blood group), anticorps complement component 4, anticorps complement C4-B, anticorps complement component 4B (Chido blood group), anticorps complement component 4A (Rodgers blood group), anticorps C4B, anticorps C4A, anticorps c4, anticorps LOC462577, anticorps C4a, anticorps C4b

Sujet: This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9.

UniProt: P0C0L4

Pathways: Système du Complément