CAMKK2
Reactivité: Humain
WB, ELISA, IHC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Titration of the CAMKK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Aliquot the CAMKK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Antigène
CAMKK2
(Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))
anticorps CAMKK, anticorps CAMKKB, anticorps 6330570N16Rik, anticorps AW061083, anticorps mKIAA0787, anticorps camk2b, anticorps fj90d04, anticorps wu:fj90d04, anticorps si:dkey-174n20.2, anticorps CAMKK2, anticorps calcium/calmodulin dependent protein kinase kinase 2, anticorps calcium/calmodulin-dependent protein kinase kinase 2, beta, anticorps calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1, anticorps calcium/calmodulin dependent protein kinase II beta, anticorps calcium/calmodulin-dependent protein kinase kinase 2, anticorps CAMKK2, anticorps Camkk2, anticorps camk2b1, anticorps CAMK2B, anticorps camkk2
Sujet
CAMKK2 belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. CAMKK2 appears to be involved in hippocampal activation of CREB1.