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CASP5 anticorps (AA 162-191)

CASP5 Reactivité: Humain WB, ELISA, IHC, FACS Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3030309
  • Antigène Voir toutes CASP5 Anticorps
    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
    Épitope
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 162-191
    Reactivité
    • 43
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 40
    • 3
    Lapin
    Clonalité
    • 33
    • 10
    Polyclonal
    Conjugué
    • 26
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp CASP5 est non-conjugé
    Application
    • 25
    • 14
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Purification
    Antigen affinity purified
    Immunogène
    A portion of amino acids 162-191 from the human protein was used as the immunogen for this Caspase-5 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CASP5 Anticorps primaire
  • Indications d'application
    Titration of the Caspase-5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot the Caspase-5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Antigène
    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
    Autre désignation
    Caspase-5 (CASP5 Produits)
    Synonymes
    anticorps ICE(rel)III, anticorps ICEREL-III, anticorps ICH-3, anticorps CASP5, anticorps caspase 5, anticorps caspase-5, anticorps CASP5, anticorps LOC100437308
    Sujet
    This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein, this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.
    UniProt
    P51878
    Pathways
    Inflammasome
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