CSF1R anticorps (AA 940-971)

N° du produit ABIN3030557

Détail du produit anti-CSF1R anticorps

Antigène: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Épitope: AA 940-971

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CSF1R est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purification: Purified

Immunogène: A portion of amino acids 940-971 from the human protein was used as the immunogen for this CSF1R antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the CSF1R antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the CSF1R antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur CSF1R

Antigène: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Autre désignation: CSF1R (CSF1R Produits)

Synonymes: anticorps AI323359, anticorps CD115, anticorps CSF-1R, anticorps Csfmr, anticorps Fim-2, anticorps Fms, anticorps M-CSF-R, anticorps M-CSFR, anticorps C-FMS, anticorps CSFR, anticorps FIM2, anticorps FMS, anticorps HDLS, anticorps PDGFRB, anticorps MGC89146, anticorps CSF-1-R, anticorps c-fms, anticorps mrfms, anticorps CSF1, anticorps M-CSF, anticorps csf1r, anticorps fms, anticorps panther, anticorps colony stimulating factor 1 receptor, anticorps macrophage colony-stimulating factor receptor, anticorps colony stimulating factor 1 receptor, a, anticorps Csf1r, anticorps CSF1R, anticorps m-csfr, anticorps csf1r, anticorps csf1ra

Sujet: CSF1R is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. This protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in the gene encoding CSF1R have been associated with a predisposition to myeloid malignancy.

UniProt: P07333

Pathways: Signalisation RTK, Inositol Metabolic Process, Cell-Cell Junction Organization