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DCLK1 anticorps (AA 153-181)

DCLK1 Reactivité: Souris WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3030771
  • Antigène Voir toutes DCLK1 Anticorps
    DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))
    Épitope
    • 15
    • 11
    • 9
    • 8
    • 7
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 153-181
    Reactivité
    • 79
    • 44
    • 13
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 76
    • 7
    • 1
    Lapin
    Clonalité
    • 70
    • 14
    Polyclonal
    Conjugué
    • 32
    • 8
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DCLK1 est non-conjugé
    Application
    • 65
    • 37
    • 18
    • 15
    • 13
    • 13
    • 8
    • 7
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antigen affinity purified
    Immunogène
    A portion of amino acids 153-181 from the mouse protein was used as the immunogen for this Dclk1 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product DCLK1 Anticorps primaire
  • Indications d'application
    Titration of the Dclk1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot the Dclk1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Antigène
    DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))
    Autre désignation
    Dclk1 (DCLK1 Produits)
    Synonymes
    anticorps DCLK1, anticorps DCAMKL1, anticorps dcamkl1, anticorps dclk1, anticorps wu:fc51f11, anticorps zgc:153709, anticorps MGC145348, anticorps CL1, anticorps CLICK1, anticorps DCDC3A, anticorps DCLK, anticorps 1700113D08Rik, anticorps 2810480F11Rik, anticorps AI836758, anticorps Click-I, anticorps Cpg16, anticorps Dcamkl1, anticorps Dcl, anticorps Dclk, anticorps mKIAA0369, anticorps Ania4, anticorps doublecortin like kinase 1, anticorps doublecortin-like kinase 1a, anticorps serine/threonine-protein kinase DCLK1, anticorps doublecortin-like kinase 2, anticorps doublecortin-like kinase 1, anticorps DCLK1, anticorps dclk1a, anticorps LOC587664, anticorps dclk2, anticorps LOC100539645, anticorps Dclk1
    Sujet
    This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been found, but the biological validity of some variants has not been determined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.
    UniProt
    Q9JLM8
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