Doublecortin anticorps (AA 107-137)

N° du produit ABIN3030770

Détail du produit anti-Doublecortin anticorps

Antigène: Doublecortin (DCX)

Épitope: AA 107-137

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Doublecortin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée (Details): Expected species reactivity: Mouse, Rat

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 107-137 from the human protein was used as the immunogen for this DCX antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the DCX antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the DCX antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur Doublecortin

Antigène: Doublecortin (DCX)

Autre désignation: DCX (DCX Produits)

Synonymes: anticorps DCX, anticorps DBCN, anticorps DC, anticorps LISX, anticorps SCLH, anticorps XLIS, anticorps Dbct, anticorps 18C15.5, anticorps doublecortin, anticorps DCX, anticorps Dcx

Sujet: In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. It contains two doublecortin domains, which bind microtubules. In addition, this protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in the gene encoding DCX are a cause of X-linked lissencephaly.

UniProt: O43602