DR1 anticorps (AA 83-112)
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- Antigène Voir toutes DR1 Anticorps
- DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))
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Épitope
- AA 83-112
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DR1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Réactivité croisée (Details)
- Expected species reactivity: Rat, Chicken
- Purification
- Antigen affinity purified
- Immunogène
- A portion of amino acids 83-112 from the human protein was used as the immunogen for this DR1 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product DR1 Anticorps primaire
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- Indications d'application
- Titration of the DR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot the DR1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Antigène
- DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))
- Autre désignation
- DR1 (Down-Regulator of Transcription 1) (DR1 Produits)
- Sujet
- This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.
- UniProt
- Q01658
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