GCLC anticorps (AA 1-30)
-
- Antigène Voir toutes GCLC Anticorps
- GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
-
Épitope
- AA 1-30
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp GCLC est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
- Purification
- Antigen affinity purified
- Immunogène
- A portion of amino acids 1-30 from the human protein was used as the immunogen for this GCLC antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product GCLC Anticorps primaire
-
-
- Indications d'application
- Titration of the GCLC antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot the GCLC antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
- Antigène
- GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
- Autre désignation
- GCLC (GCLC Produits)
- Sujet
- Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.
- UniProt
- P48506
- Pathways
- Cell RedoxHomeostasis
-