Glypican 3 anticorps (AA 529-560)
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- Antigène Voir toutes Glypican 3 (GPC3) Anticorps
- Glypican 3 (GPC3)
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Épitope
- AA 529-560
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Glypican 3 est non-conjugé
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Application
- Immunofluorescence (IF), Western Blotting (WB), ELISA
- Purification
- Purified
- Immunogène
- A portion of amino acids 529-560 from the human protein was used as the immunogen for this GPC3 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product GPC3 Anticorps primaire
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- Indications d'application
- Titration of the GPC3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:10-1:50,Western blot: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot the GPC3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Antigène
- Glypican 3 (GPC3)
- Autre désignation
- GPC3 (GPC3 Produits)
- Synonymes
- anticorps GPC3, anticorps sgb, anticorps dgsx, anticorps sdys, anticorps sgbs, anticorps oci-5, anticorps sgbs1, anticorps DGSX, anticorps GTR2-2, anticorps MXR7, anticorps OCI-5, anticorps SDYS, anticorps SGB, anticorps SGBS, anticorps SGBS1, anticorps Glypican-3, anticorps glypican 3, anticorps gpc3, anticorps GPC3, anticorps Gpc3
- Sujet
- GPC3 is a cell surface proteoglycan that bears heparan sulfate. This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage. These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition. Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.
- UniProt
- P51654
- Pathways
- Glycosaminoglycan Metabolic Process
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