GSK3 beta anticorps (AA 30-59)

N° du produit ABIN3031094

Détail du produit anti-GSK3 beta anticorps

Antigène: GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))

Épitope: AA 30-59

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSK3 beta est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Réactivité croisée (Details): Expected species reactivity: Human, Rat

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 30-59 from the mouse protein was used as the immunogen for this Gsk3b antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Gsk3b antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Gsk3b antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur GSK3 beta

Antigène: GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))

Autre désignation: Gsk3b (GSK3b Produits)

Synonymes: anticorps GSK3, anticorps GSK-3, anticorps C86142, anticorps GSK-3beta, anticorps 7330414F15Rik, anticorps 8430431H08Rik, anticorps GSK3beta, anticorps fk80d11, anticorps GSK-3[b], anticorps wu:fb68h05, anticorps wu:fk80d11, anticorps gsk-3, anticorps gsk3, anticorps gsk3-beta, anticorps gsk3beta, anticorps xgsk-3, anticorps glycogen synthase kinase 3 beta, anticorps glycogen synthase kinase 3 beta L homeolog, anticorps GSK3B, anticorps Gsk3b, anticorps gsk3b, anticorps gsk3b.L

Sujet: Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. May phosphorylate MUC1 and decrease the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin. Phosphorylates SNAI1 (By similarity).

UniProt: Q9WV60

Pathways: Signalisation WNT, Signalisation Hedgehog, Fc-epsilon Receptor Signaling Pathway, Cellular Glucan Metabolic Process, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Autophagy, BCR Signaling, L'effet Warburg