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IL-10 anticorps (AA 27-53)

IL10 Reactivité: Humain WB, ELISA, IHC, FACS Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3031441
  • Antigène Voir toutes IL-10 (IL10) Anticorps
    IL-10 (IL10) (Interleukin 10 (IL10))
    Épitope
    • 36
    • 16
    • 16
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 27-53
    Reactivité
    • 146
    • 93
    • 50
    • 19
    • 17
    • 11
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 121
    • 74
    • 66
    • 4
    • 2
    • 1
    Lapin
    Clonalité
    • 141
    • 123
    • 1
    Polyclonal
    Conjugué
    • 161
    • 33
    • 12
    • 11
    • 11
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IL-10 est non-conjugé
    Application
    • 164
    • 125
    • 76
    • 66
    • 42
    • 29
    • 28
    • 18
    • 16
    • 15
    • 14
    • 14
    • 13
    • 12
    • 12
    • 8
    • 8
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Réactivité croisée (Details)
    Expected species reactivity: Primate
    Purification
    Antigen affinity purified
    Immunogène
    A portion of amino acids 27-53 from the human protein was used as the immunogen for this IL-10 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product IL10 Anticorps primaire
  • Indications d'application
    Titration of the IL-10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot the IL-10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Antigène
    IL-10 (IL10) (Interleukin 10 (IL10))
    Autre désignation
    IL-10 (IL10 Produits)
    Synonymes
    anticorps CSIF, anticorps GVHDS, anticorps IL-10, anticorps IL10A, anticorps TGIF, anticorps Il-10, anticorps IL10X, anticorps interleukin 10, anticorps IL10, anticorps Il10
    Sujet
    The protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
    UniProt
    P22301
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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