MAVS anticorps (AA 1-30)
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- Antigène Voir toutes MAVS Anticorps
- MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
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Épitope
- AA 1-30
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MAVS est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- Antigen affinity purified
- Immunogène
- A portion of amino acids 1-30 from the mouse protein was used as the immunogen for this Ips-1 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product MAVS Anticorps primaire
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- Indications d'application
- Titration of the Ips-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot the Ips-1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Antigène
- MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
- Autre désignation
- Ips-1 (MAVS Produits)
- Sujet
- Required for innate immune defense against viruses. Acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis (By similarity).
- UniProt
- Q8VCF0
- Pathways
- Activation of Innate immune Response, Inositol Metabolic Process, Hepatitis C
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