ISL1 anticorps (AA 156-185)

N° du produit ABIN3031505

Détail du produit anti-ISL1 anticorps

Antigène: ISL1 (ISL LIM Homeobox 1 (ISL1))

Épitope: AA 156-185

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ISL1 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): Expected species reactivity: Rat, Chicken, Zebrafish

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 156-185 from the human protein was used as the immunogen for this ISL1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the ISL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the ISL1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur ISL1

Antigène: ISL1 (ISL LIM Homeobox 1 (ISL1))

Autre désignation: ISL1 (ISL1 Produits)

Synonymes: anticorps Xisl-1, anticorps Xislet-1, anticorps islet1, anticorps ISLET-1, anticorps ISLET1, anticorps Isl-1, anticorps islet-1, anticorps isl-1=homeobox, anticorps Islet-1, anticorps ISL LIM homeobox 1 S homeolog, anticorps ISL LIM homeobox 1, anticorps ISL1 transcription factor, LIM/homeodomain, anticorps isl1.S, anticorps ISL1, anticorps Isl1, anticorps isl1

Sujet: ISL1 is a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.

UniProt: P61371

Pathways: Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding