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JMJD2D anticorps (AA 484-516)

KDM4D Reactivité: Humain ELISA, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3031654
  • Antigène Voir toutes JMJD2D (KDM4D) Anticorps
    JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
    Épitope
    • 7
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 484-516
    Reactivité
    • 33
    • 3
    • 2
    • 1
    Humain
    Hôte
    • 33
    Lapin
    Clonalité
    • 33
    Polyclonal
    Conjugué
    • 16
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp JMJD2D est non-conjugé
    Application
    • 22
    • 17
    • 5
    • 3
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Purification
    Purified
    Immunogène
    A portion of amino acids 484-516 from the human protein was used as the immunogen for this JMJD2D antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product KDM4D Anticorps primaire
  • Indications d'application
    Titration of the JMJD2D antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot the JMJD2D antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Antigène
    JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
    Autre désignation
    JMJD2D (KDM4D) (KDM4D Produits)
    Synonymes
    anticorps JMJD2D, anticorps 4932416A15, anticorps Jmjd2d, anticorps KDM4D, anticorps lysine demethylase 4D, anticorps lysine-specific demethylase 4D, anticorps lysine (K)-specific demethylase 4D, anticorps KDM4D, anticorps LOC524768, anticorps Kdm4d, anticorps LOC617971, anticorps LOC100067461, anticorps LOC698455, anticorps LOC100514356
    Sujet
    Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.
    UniProt
    Q6B0I6
    Pathways
    L'effet Warburg
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