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Kdm6b anticorps (AA 954-987)

Kdm6b Reactivité: Humain, Souris WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3031662
  • Antigène Voir toutes Kdm6b Anticorps
    Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))
    Épitope
    • 9
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 954-987
    Reactivité
    • 43
    • 24
    • 10
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain, Souris
    Hôte
    • 46
    • 1
    • 1
    Lapin
    Clonalité
    • 47
    • 1
    Polyclonal
    Conjugué
    • 31
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Kdm6b est non-conjugé
    Application
    • 36
    • 20
    • 11
    • 6
    • 6
    • 5
    • 3
    Western Blotting (WB), ELISA
    Purification
    Purified
    Immunogène
    A portion of amino acids 954-987 from the mouse protein was used as the immunogen for this JMJD3 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product Kdm6b Anticorps primaire
  • Indications d'application
    Titration of the JMJD3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot the JMJD3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Antigène
    Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))
    Autre désignation
    JMJD3 (KDM6B) (Kdm6b Produits)
    Synonymes
    anticorps jmjd3, anticorps kdm6b, anticorps si:ch211-237l4.7, anticorps 1700064E03Rik, anticorps BC038313, anticorps Jmjd3, anticorps mKIAA0346, anticorps JMJD3, anticorps lysine (K)-specific demethylase 6B, anticorps lysine demethylase 6B, anticorps lysine (K)-specific demethylase 6B, b, anticorps KDM1 lysine (K)-specific demethylase 6B, anticorps kdm6b, anticorps KDM6B, anticorps kdm6bb, anticorps Kdm6b
    Sujet
    Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.
    UniProt
    Q5NCY0
    Pathways
    L'effet Warburg
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