MAPK10 anticorps (AA 1-30)

N° du produit ABIN3031827

Cet anticorps anti-MAPK10 Polyclonal Lapin (ABIN3031827) détecte spécifiquement MAPK10 dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour MAPK10 anticorps (AA 1-30) (ABIN3031827)

Antigène: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPK10 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-MAPK10 anticorps

Épitope: AA 1-30

Purification: Purified

Immunogène: A portion of amino acids 1-30 from the human protein was used as the immunogen for this JNK3 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the JNK3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the JNK3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur MAPK10

Antigène: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Autre désignation: JNK3

Sujet: JNK3 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kinase 5 can phosphorylate and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis.

UniProt: P53779

Pathways: Signalisation MAPK, Signalisation WNT, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades