LRP5 anticorps (AA 1538-1567)
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- Antigène Voir toutes LRP5 Anticorps
- LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
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Épitope
- AA 1538-1567
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp LRP5 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- Purified
- Immunogène
- A portion of amino acids 1538-1567 from the human protein was used as the immunogen for this LRP5 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product LRP5 Anticorps primaire
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- Indications d'application
- Titration of the LRP5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot the LRP5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Antigène
- LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
- Autre désignation
- LRP5 (LRP5 Produits)
- Synonymes
- anticorps Xlrp5, anticorps bmnd1, anticorps evr1, anticorps evr4, anticorps hbm, anticorps lr3, anticorps lrp5-A, anticorps lrp7, anticorps oppg, anticorps ops, anticorps opta1, anticorps vbch2, anticorps LRP5, anticorps LRP6, anticorps BMND1, anticorps EVR1, anticorps EVR4, anticorps HBM, anticorps LR3, anticorps LRP7, anticorps OPPG, anticorps OPS, anticorps OPTA1, anticorps VBCH2, anticorps mKIAA4142, anticorps low-density lipoprotein receptor-related protein 5, anticorps LDL receptor related protein 5, anticorps LDL receptor related protein 5 L homeolog, anticorps low density lipoprotein receptor-related protein 5, anticorps LDL receptor related protein 5 like, anticorps LOC100147353, anticorps LRP5, anticorps lrp5.L, anticorps lrp5, anticorps Lrp5, anticorps LRP5L
- Sujet
- Low density lipoprotein (LDL) receptor-related protein (LRP), a member of the LDL receptor family, binds multiple classes of ligands and has been implicated in a broad range of normal and disease processes involving lipid metabolism, protease clearance, and cell migration. Structurally, members of the LDLR family share homology within their extracellular domains, which are highlighted by the presence of clusters of ligand-binding repeats. LRP is a large endocytic receptor that participates in several biological pathways and plays prominent roles in lipoprotein metabolism and in the catabolism of proteinases involved in coagulation and fibrinolysis. LRP also mediates the cellular entry of certain viruses and toxins and facilitates the activation of various lysosomal enzymes. All LRPs are expressed in the central nervous system and, for most receptors, animal models have shown that they are indispensable for successful neurodevelopment. The mechanisms by which they regulate the formation of the nervous system are varied and include the transduction of extracellular signals and the modulation of intracellular signal propagation, as well as cargo transport, the function most commonly attributed to this gene family.
- UniProt
- O75197
- Pathways
- Signalisation WNT, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation
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