Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

MAVS anticorps (AA 477-505)

MAVS Reactivité: Humain WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3031816
  • Antigène Voir toutes MAVS Anticorps
    MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
    Épitope
    • 15
    • 13
    • 9
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 477-505
    Reactivité
    • 48
    • 38
    • 4
    • 2
    • 1
    Humain
    Hôte
    • 69
    • 7
    Lapin
    Clonalité
    • 71
    • 5
    Polyclonal
    Conjugué
    • 34
    • 6
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MAVS est non-conjugé
    Application
    • 68
    • 36
    • 13
    • 13
    • 11
    • 9
    • 9
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antigen affinity purified
    Immunogène
    A portion of amino acids 477-505 from the human protein was used as the immunogen for this MAVS antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MAVS Anticorps primaire
  • Indications d'application
    Titration of the MAVS antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot the MAVS antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Antigène
    MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
    Autre désignation
    MAVS (MAVS Produits)
    Synonymes
    anticorps CARDIF, anticorps IPS-1, anticorps IPS1, anticorps VISA, anticorps D430028G21Rik, anticorps Visa, anticorps cardif, anticorps wu:fj20d04, anticorps zgc:158392, anticorps mitochondrial antiviral signaling protein, anticorps MAVS, anticorps Mavs, anticorps mavs
    Sujet
    Double-stranded RNA viruses are recognized in a cell type-dependent manner by the transmembrane receptor TLR3 or by the cytoplasmic RNA helicases MDA5 and RIGI. These interactions initiate signaling pathways that differ in their initial steps but converge in the activation of the protein kinases IKKA and IKKB which activate NFKB, or TBK1 and IKKE (IKBKE, MIM 605048), which activate IRF3. Activated IRF3 and NFKB induce transcription of IFNB. For the TLR3 pathway, the intermediary molecule before the pathways converge is the cytoplasmic protein TRIF. For RIGI, the intermediary protein is mitochondria-bound IPS1.
    UniProt
    Q7Z434
    Pathways
    Activation of Innate immune Response, Inositol Metabolic Process, Hepatitis C
Vous êtes ici:
Support technique