MGMT anticorps (AA 156-182)

N° du produit ABIN3032088

Détail du produit anti-MGMT anticorps

Antigène: MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))

Épitope: AA 156-182

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MGMT est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Purification: Purified

Immunogène: A portion of amino acids 156-182 from the human protein was used as the immunogen for this MGMT antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the MGMT antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the MGMT antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur MGMT

Antigène: MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))

Autre désignation: MGMT (MGMT Produits)

Synonymes: anticorps AGT, anticorps AI267024, anticorps Agat, anticorps O-6-methylguanine-DNA methyltransferase, anticorps MGMT, anticorps Mgmt

Sujet: MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. This protein repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the protein is irreversibly inactivated.

UniProt: P16455

Pathways: Réparation de l'ADN, Positive Regulation of Response to DNA Damage Stimulus