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MIB1 anticorps (AA 13-42)

MIB1 Reactivité: Humain ELISA, WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3031774
  • Antigène Voir toutes MIB1 Anticorps
    MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
    Épitope
    • 15
    • 8
    • 6
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 13-42
    Reactivité
    • 68
    • 15
    • 5
    • 4
    • 1
    • 1
    Humain
    Hôte
    • 68
    • 5
    • 2
    Lapin
    Clonalité
    • 63
    • 12
    Polyclonal
    Conjugué
    • 26
    • 8
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MIB1 est non-conjugé
    Application
    • 38
    • 31
    • 22
    • 14
    • 14
    • 9
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Réactivité croisée (Details)
    Expected species reactivity: Mouse, Zebrafish, Xenopus
    Purification
    Purified
    Immunogène
    A portion of amino acids 13-42 from the human protein was used as the immunogen for this Mib1 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MIB1 Anticorps primaire
  • Indications d'application
    Titration of the Mib1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:20-1:100,IHC (Paraffin): 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot the Mib1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Antigène
    MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
    Autre désignation
    Mib1 (Mindbomb) (MIB1 Produits)
    Sujet
    MIB is an E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. This protein positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. MIB probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.
    UniProt
    Q86YT6
    Pathways
    SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2
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