MUSK anticorps (AA 829-859)

N° du produit ABIN3031878

Détail du produit anti-MUSK anticorps

Antigène: MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))

Épitope: AA 829-859

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MUSK est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purification: Purified

Immunogène: A portion of amino acids 829-859 from the human protein was used as the immunogen for this MUSK antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the MUSK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Flow Cytometry: 1:10-1:50,Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the MUSK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur MUSK

Antigène: MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))

Autre désignation: MUSK (MUSK Produits)

Synonymes: anticorps unp, anticorps fj98e12, anticorps zgc:63467, anticorps wu:fj98e12, anticorps si:dz46m7.2, anticorps si:dz57f23.3, anticorps si:busm1-57f23.3, anticorps musk-A, anticorps MuSK, anticorps MUSK, anticorps Mdk4, anticorps Mlk, anticorps Nsk1, anticorps Nsk2, anticorps Nsk3, anticorps muscle, anticorps muscle associated receptor tyrosine kinase, anticorps muscle, skeletal, receptor tyrosine kinase, anticorps muscle associated receptor tyrosine kinase S homeolog, anticorps MUSK, anticorps musk, anticorps musk.S, anticorps Musk

Sujet: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).

UniProt: O15146

Pathways: Signalisation RTK, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development