MUSK anticorps

N° du produit ABIN3031879

Détail du produit anti-MUSK anticorps

Antigène: MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MUSK est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Purification: Purified

Immunogène: This MUSK antibody was produced from rabbits immunized with human MUSK recombinant protein.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the MUSK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the MUSK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur MUSK

Antigène: MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))

Autre désignation: MUSK (MUSK Produits)

Synonymes: anticorps unp, anticorps fj98e12, anticorps zgc:63467, anticorps wu:fj98e12, anticorps si:dz46m7.2, anticorps si:dz57f23.3, anticorps si:busm1-57f23.3, anticorps musk-A, anticorps MuSK, anticorps MUSK, anticorps Mdk4, anticorps Mlk, anticorps Nsk1, anticorps Nsk2, anticorps Nsk3, anticorps muscle, anticorps muscle associated receptor tyrosine kinase, anticorps muscle, skeletal, receptor tyrosine kinase, anticorps muscle associated receptor tyrosine kinase S homeolog, anticorps MUSK, anticorps musk, anticorps musk.S, anticorps Musk

Sujet: MuSK activates signaling cascades responsible for many aspects of synapse formation, including the organization of the postsynaptic membrane, synapse-specific transcription, and presynaptic differentiation. MuSK also mediates agrin-induced aggregation of acetylcholine receptors at the mature vertebrate neuromuscular junction and also during synapse formation. It has been shown that a majority of AChR Ab-seronegative myasthenia gravis patients possess serum autoantibodies against MuSK.

UniProt: O15146

Pathways: Signalisation RTK, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development