MYB anticorps (AA 506-534)
-
- Antigène Voir toutes MYB Anticorps
- MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
-
Épitope
- AA 506-534
-
Reactivité
- Souris
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp MYB est non-conjugé
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- Antigen affinity purified
- Immunogène
- A portion of amino acids 506-534 from the human protein was used as the immunogen for this Myb antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product MYB Anticorps primaire
-
-
- Indications d'application
- Titration of the Myb antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Western blot: 1:1000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot the Myb antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
- Antigène
- MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
- Autre désignation
- Myb (MYB Produits)
- Sujet
- Myb is a transcriptional activator, DNA-binding protein that recognizes the sequence 5'-YAAC[GT]G-3'. It participates in the control of proliferation and differentiation of hematopoietic progenitor cells. Myb is a transcription factor related to Myc, and is expressed predominantly in haematopoietic cells and immature gastroepithelial cells. TRAF7 stimulates the sumoylation of Myb at Lys-523 and Lys-499, which are the same sites as those used for PIASy-induced sumoylation. A correlation has been established between reduction in sumoylation of Myb and increase in transcriptional activation. Negative influence on transactivation properties by the negative regulatory domain region of c-Myb depends on upon sumoylation.
- UniProt
- P10242
- Pathways
- Chromatin Binding, Positive Regulation of Immune Effector Process
-