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Nanog anticorps (AA 267-292)

NANOG Reactivité: Humain WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3031938
  • Antigène Voir toutes Nanog (NANOG) Anticorps
    Nanog (NANOG) (Nanog Homeobox (NANOG))
    Épitope
    • 16
    • 16
    • 12
    • 10
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 267-292
    Reactivité
    • 139
    • 59
    • 22
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 126
    • 19
    • 3
    • 1
    Lapin
    Clonalité
    • 121
    • 28
    Polyclonal
    Conjugué
    • 78
    • 9
    • 8
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp Nanog est non-conjugé
    Application
    • 110
    • 60
    • 44
    • 42
    • 26
    • 26
    • 21
    • 18
    • 18
    • 15
    • 8
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Purification
    Antigen affinity purified
    Immunogène
    A portion of amino acids 267-292 from the human protein was used as the immunogen for this NANOG antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product NANOG Anticorps primaire
  • Indications d'application
    Titration of the NANOG antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot the NANOG antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Antigène
    Nanog (NANOG) (Nanog Homeobox (NANOG))
    Autre désignation
    NANOG (NANOG Produits)
    Synonymes
    anticorps 2410002E02Rik, anticorps ENK, anticorps ecat4, anticorps NANOG, anticorps hacp, anticorps wu:fd19e04, anticorps wu:fd20a07, anticorps zgc:193933, anticorps Nanog homeobox, anticorps nanog homeobox, anticorps Nanog, anticorps NANOG, anticorps nanog
    Sujet
    NANOG is a Ttranscription regulator involved in inner cell mass and embryonic stem (ES) cels proliferation and self-renewal. It imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. This protein blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. NANOG acts as a transcriptional activator or repressor. It binds optimally to the DNA consensus sequence 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, this protein promotes cells to enter into S phase and proliferation.
    UniProt
    Q9H9S0
    Pathways
    Stem Cell Maintenance
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