NCAPH2 anticorps (AA 198-227)

N° du produit ABIN3032026

Détail du produit anti-NCAPH2 anticorps

Antigène: NCAPH2 (Non-SMC Condensin II Complex, Subunit H2 (NCAPH2))

Épitope: AA 198-227

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCAPH2 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Purified

Immunogène: A portion of amino acids 198-227 from the human protein was used as the immunogen for this NCAPH2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the NCAPH2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the NCAPH2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur NCAPH2

Antigène: NCAPH2 (Non-SMC Condensin II Complex, Subunit H2 (NCAPH2))

Autre désignation: NCAPH2 (NCAPH2 Produits)

Synonymes: anticorps MGC81656, anticorps CAPH2, anticorps si:dkey-202b22.2, anticorps non-SMC condensin II complex subunit H2, anticorps non-SMC condensin II complex subunit H2 L homeolog, anticorps non-SMC condensin II complex, subunit H2, anticorps NCAPH2, anticorps ncaph2.L, anticorps ncaph2, anticorps Ncaph2

Sujet: Structural maintenance of chromosomes (SMC) and non-SMC condensin proteins associate into complexes that have been implicated in the process of chromosome condensation. A crucial prerequisite for accurate segregation of replicated sister chromatids is the condensation of the chromosomes into a manageable form prior to metaphase. The condensin I complex consists of two SMC subunits, SMC2 and SMC4, and three non-SMC subunits, CAP-H, CAP-G, and CAP-D2. An alternative complex, the condensin II complex, contains alternate non-SMC subunits, CAP-G2, CAP-H2, and CAP-D3. CAP-H2 is also known as Non-SMC condensin II complex, subunit H2 (NCAPH2) or kleisin beta isoform 2. The three non-SMC subunits in the condensing complexes form a regulatory subcomplex that is required to activate the SMC ATPases and to promote mitosis-specific chromatin binding of the holocomplex. The precise individual functions of each non-SMC protein in activation remain to be determined.

UniProt: Q6IBW4