NLRP4 anticorps (AA 121-149)

N° du produit ABIN3032022

Détail du produit anti-NLRP4 anticorps

Antigène: NLRP4 (NLR Family, Pyrin Domain Containing 4 (NLRP4))

Épitope: AA 121-149

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP4 est non-conjugé

Application: ELISA, Western Blotting (WB)

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 121-149 from the human protein was used as the immunogen for this NLRP4 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the NLRP4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the NLRP4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur NLRP4

Antigène: NLRP4 (NLR Family, Pyrin Domain Containing 4 (NLRP4))

Autre désignation: NLRP4 (NLRP4 Produits)

Synonymes: anticorps CLR19.5, anticorps CT58, anticorps NALP4, anticorps PAN2, anticorps PYPAF4, anticorps RNH2, anticorps Nalp4, anticorps Nlrp4e, anticorps RGD1563529, anticorps NLR family pyrin domain containing 4, anticorps NLR family, pyrin domain containing 4, anticorps NLRP4, anticorps Nlrp4

Sujet: NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV, MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1, MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).

UniProt: Q96MN2

Pathways: Inflammasome