Neuregulin 2 anticorps (AA 830-855)

N° du produit ABIN3031976

Détail du produit anti-Neuregulin 2 anticorps

Antigène: Neuregulin 2 (NRG2)

Épitope: AA 830-855

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neuregulin 2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée (Details): Expected species reactivity: Rat

Purification: Purified

Immunogène: A portion of amino acids 830~855 from the human protein was used as the immunogen for this NRG2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the NRG2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the NRG2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur Neuregulin 2

Antigène: Neuregulin 2 (NRG2)

Autre désignation: NRG2 (NRG2 Produits)

Synonymes: anticorps NRG2, anticorps Don1, anticorps NTAK, anticorps DON1, anticorps HRG2, anticorps NTAK_alpha2a, anticorps Ntak, anticorps neuregulin 2, anticorps NRG2, anticorps Nrg2

Sujet: Neuregulin 2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the Erbb family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1 (NRG1), another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. There are six NRG2 alternatively spliced transcripts which are variable between the epidermal growth factor-like (EGF-like) and the transmembrane domains. The gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease.

UniProt: O14511

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway