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P-Glycoprotein anticorps (AA 647-677)

Reactivité: Humain WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3032111
  • Antigène Tous les produits P-Glycoprotein
    P-Glycoprotein
    Épitope
    • 3
    • 2
    • 1
    • 1
    AA 647-677
    Reactivité
    • 21
    • 10
    • 9
    • 2
    Humain
    Hôte
    • 15
    • 7
    Lapin
    Clonalité
    • 15
    • 6
    • 1
    Polyclonal
    Conjugué
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp P-Glycoprotein est non-conjugé
    Application
    • 11
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Purified
    Immunogène
    A portion of amino acids 647-677 from the human protein was used as the immunogen for this P-Glycoprotein antibody.
    Isotype
    Ig Fraction
  • Indications d'application
    Titration of the P-Glycoprotein antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot the P-Glycoprotein antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Antigène
    P-Glycoprotein
    Abstract
    P-Glycoprotein Produits
    Synonymes
    anticorps ABC20, anticorps CD243, anticorps CLCS, anticorps GP170, anticorps MDR1, anticorps P-GP, anticorps PGY1, anticorps Abcb1, anticorps Mdr1a, anticorps ABCB1, anticorps ABCB4, anticorps CMDR1, anticorps xemdr, anticorps ATP binding cassette subfamily B member 1, anticorps ATP binding cassette subfamily B member 1A, anticorps ATP binding cassette subfamily B member 1 L homeolog, anticorps ABCB1, anticorps Abcb1a, anticorps abcb1.L
    Sujet
    The membrane-associated ABCB1 protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. ABCB1 is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
    UniProt
    P08183
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