SQSTM1 anticorps (AA 317-346)
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- Antigène Voir toutes SQSTM1 Anticorps
- SQSTM1 (Sequestosome 1 (SQSTM1))
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Épitope
- AA 317-346
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Reactivité
- Humain, Green Monkey
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SQSTM1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- Réactivité croisée (Details)
- Expected species reactivity: Mouse, Rat
- Purification
- Antigen affinity purified
- Immunogène
- A portion of amino acids 317-346 from the human protein was used as the immunogen for this p62 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product SQSTM1 Anticorps primaire
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anti-Sequestosome 1 (SQSTM1) (AA 317-346) antibody
SQSTM1 Reactivité: Humain, Souris WB, IF, IHC (p) Hôte: Lapin Polyclonal RB4614 unconjugated
anti-Sequestosome 1 (SQSTM1) antibodyKO Validated SQSTM1 Reactivité: Humain WB, IF, IP, IHC (p), FACS, ICC, PLA Hôte: Lapin Polyclonal unconjugated
anti-Sequestosome 1 (SQSTM1) (AA 51-150) antibodySQSTM1 Reactivité: Humain, Souris, Rat, Boeuf (Vache) WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Sequestosome 1 (SQSTM1) (AA 232-356) antibodySQSTM1 Reactivité: Humain WB, IHC, ELISA, FACS Hôte: Souris Monoclonal 5H7E2 unconjugated
anti-Sequestosome 1 (SQSTM1) (AA 1-440) antibodySQSTM1 Reactivité: Humain WB, ELISA, IF Hôte: Souris Monoclonal 2C11 unconjugated
anti-Sequestosome 1 (SQSTM1) (AA 1-440) antibodySQSTM1 Reactivité: Humain WB, IHC, IF, IP Hôte: Lapin Polyclonal unconjugated
anti-Sequestosome 1 (SQSTM1) (AA 136-400) antibodySQSTM1 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Sequestosome 1 (SQSTM1) (C-Term) antibodySQSTM1 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Sequestosome 1 (SQSTM1) antibodySQSTM1 Reactivité: Humain, Singe WB, IHC, IF, IHC (p), FACS Hôte: Souris Monoclonal 5A2 unconjugated
anti-Sequestosome 1 (SQSTM1) antibodyKO Validated SQSTM1 Reactivité: Humain WB, IHC, IF, IP Hôte: Lapin Monoclonal unconjugated
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- Indications d'application
- Titration of the p62 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot the p62 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Antigène
- SQSTM1 (Sequestosome 1 (SQSTM1))
- Autre désignation
- p62 (SQSTM1) (SQSTM1 Produits)
- Synonymes
- anticorps SQSTM1, anticorps sqstm1, anticorps MGC79491, anticorps A170, anticorps OSIL, anticorps PDB3, anticorps ZIP3, anticorps p60, anticorps p62, anticorps p62B, anticorps OSF-6, anticorps Osi, anticorps STAP, anticorps ZIP, anticorps sb:cb621, anticorps zgc:85784, anticorps sequestosome 1, anticorps sequestosome 1 L homeolog, anticorps SQSTM1, anticorps sqstm1, anticorps Sqstm1, anticorps sqstm1.L
- Sujet
- SQSTM1/p62 is an adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. This protein may play a role in titin/TTN downstream signaling in muscle cells, and may also regulate signaling cascades through ubiquitination. This protein is involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. SQSTM1/p62 also appears to play a role in macroautophagic removal of intracellular protein aggregates. Cellular depletion studies of SQSTM1/p62 have indicated a role for association with LC3 and aggregate proteins in order to facilitate normal formation of the autophagosome.
- UniProt
- Q13501
- Pathways
- Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Autophagy
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