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PDK4 anticorps (AA 382-410)

PDK4 Reactivité: Humain, Souris WB, ELISA, IHC, IF, mIHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3028963
  • Antigène Voir toutes PDK4 Anticorps
    PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))
    Épitope
    • 15
    • 15
    • 8
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 382-410
    Reactivité
    • 76
    • 50
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 75
    • 13
    Lapin
    Clonalité
    • 79
    • 11
    Polyclonal
    Conjugué
    • 42
    • 9
    • 6
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PDK4 est non-conjugé
    Application
    • 74
    • 48
    • 28
    • 13
    • 13
    • 9
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Multiplex Immunohistochemistry (mIHC)
    Purification
    Purified
    Immunogène
    A portion of amino acids 382-410 from the human protein was used as the immunogen for this PDK4 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PDK4 Anticorps primaire
  • Indications d'application
    Titration of the PDK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:100,Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot the PDK4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Sirait-Fischer, Olesch, Fink, Berkefeld, Huard, Schmid, Takeda, Brüne, Weigert: "Immune Checkpoint Blockade Improves Chemotherapy in the PyMT Mammary Carcinoma Mouse Model." dans: Frontiers in oncology, Vol. 10, pp. 1771, (2020) (PubMed).

  • Antigène
    PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))
    Autre désignation
    PDK4 (PDK4 Produits)
    Synonymes
    anticorps AV005916, anticorps pyruvate dehydrogenase kinase 4, anticorps pyruvate dehydrogenase kinase, isoenzyme 4, anticorps pdk4, anticorps PDK4, anticorps Pdk4
    Sujet
    PDK4 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
    UniProt
    Q16654
    Pathways
    Signalisation PI3K-Akt, Signalisation Hedgehog, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg
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