Retinoblastoma Protein (Rb) anticorps (pSer780)
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- Antigène Voir toutes Retinoblastoma Protein (Rb) (Rb Protein) Anticorps
- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
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Épitope
- pSer780
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Retinoblastoma Protein (Rb) est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC), Dot Blot (DB)
- Réactivité croisée (Details)
- Expected species reactivity: Mouse, Rat
- Purification
- Antigen affinity purified
- Immunogène
- This phospho-Rb antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS780 of human Rb.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product Rb Protein Anticorps primaire
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anti-Retinoblastoma Protein (Rb Protein) (AA 858-886) antibody
Rb Protein Reactivité: Humain WB, ELISA, IHC, FACS Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (pSer811) antibodyRb Protein Reactivité: Humain ELISA, IHC, IF, DB Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (AA 586-615) antibodyRb Protein Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (Cleavage Site) antibodyRb Protein Reactivité: Humain, Souris WB, IHC Hôte: Souris Monoclonal 172C1094 unconjugated
anti-Retinoblastoma Protein (Rb Protein) (pSer608) antibodyRb Protein Reactivité: Humain ELISA, IHC, DB Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (pSer788) antibodyRb Protein Reactivité: Humain ELISA, IHC, DB Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) antibodyRb Protein Reactivité: Humain ELISA, IHC Hôte: Souris Monoclonal 7E4B8 unconjugated
anti-Retinoblastoma Protein (Rb Protein) (AA 251-268) antibodyRb Protein Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Singe, Porc, Cheval, Roussette (Chauve-souris) WB Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (N-Term) antibodyRb Protein Reactivité: Humain, Souris, Singe WB Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (C-Term) antibodyRb Protein Reactivité: Humain, Boeuf (Vache), Chien, Porc, Roussette (Chauve-souris), Cobaye WB Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
- Titration of the phospho-Rb antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500,IHC (Paraffin): 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot the phospho-Rb antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Antigène
- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
- Autre désignation
- Retinoblastoma / Rb (Rb Protein Produits)
- Sujet
- RB1 likely acts as a regulator of other genes. It forms a complex with adenovirus E1A and with SV40 large T antigen, acts as a tumor suppressor, and may bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. RB1 is a potent inhibitor of E2F-mediated trans-activation, and also recruits and targets histone methyltransferase SUV39H1 leading to epigenetic transcriptional repression. This protein inhibits the intrinsic kinase activity of TAF1. Defects in RB1 are the cause of childhood cancer retinoblastoma (RB), a congenital malignant tumor that arises from the nuclear layers of the retina. Defects in RB1 are also a cause of bladder cancer and osteogenic sarcoma.
- UniProt
- P06400
- Pathways
- Mitotic G1-G1/S Phases
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