TERT anticorps (pTyr707)

N° du produit ABIN3029107

Détail du produit anti-TERT anticorps

Antigène: TERT (Telomerase Reverse Transcriptase (TERT))

Épitope: pTyr707

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TERT est non-conjugé

Application: ELISA, Dot Blot (DB), Immunofluorescence (IF)

Purification: Antigen affinity purified

Immunogène: This phospho-TERT antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY707 of human TERT.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the phospho-TERT antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:10-1:50,Dot blot: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the phospho-TERT antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur TERT

Antigène: TERT (Telomerase Reverse Transcriptase (TERT))

Autre désignation: TERT (TERT Produits)

Synonymes: anticorps CMM9, anticorps DKCA2, anticorps DKCB4, anticorps EST2, anticorps PFBMFT1, anticorps TCS1, anticorps TP2, anticorps TRT, anticorps hEST2, anticorps hTRT, anticorps chTERT, anticorps Tert, anticorps ATTERT, anticorps F5E19.190, anticorps F5E19_190, anticorps telomerase reverse transcriptase, anticorps tert, anticorps TR, anticorps est2, anticorps tcs1, anticorps telomerase, anticorps tert-A, anticorps tp2, anticorps trt, anticorps xTERT, anticorps telomerase reverse transcriptase, anticorps Telomerase Reverse Transcriptase, anticorps Tertp, anticorps Telomerase catalytic subunit, anticorps telomerase reverse transcriptase L homeolog, anticorps TERT, anticorps trt-1, anticorps Tert, anticorps tert, anticorps CMU_003490, anticorps VDBG_04487, anticorps GL50803_16225, anticorps tert.L

Sujet: Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks.

UniProt: O14746

Pathways: Telomere Maintenance