PITX2 anticorps (AA 122-151)

N° du produit ABIN3032141

Détail du produit anti-PITX2 anticorps

Antigène: PITX2 (Paired-Like Homeodomain 2 (PITX2))

Épitope: AA 122-151

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PITX2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Réactivité croisée (Details): Expected species reactivity: Mouse, Rat, Chicken, Zebrafish, Xenopus

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 122-151 from the human protein was used as the immunogen for this PITX2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the PITX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:10-1:50,Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the PITX2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur PITX2

Antigène: PITX2 (Paired-Like Homeodomain 2 (PITX2))

Autre désignation: PITX2 (PITX2 Produits)

Synonymes: anticorps ARP1, anticorps Brx1, anticorps IDG2, anticorps IGDS, anticorps IGDS2, anticorps IHG2, anticorps IRID2, anticorps Otlx2, anticorps PTX2, anticorps RGS, anticorps RIEG, anticorps RIEG1, anticorps RS, anticorps 9430085M16Rik, anticorps Brx1a, anticorps Brx1b, anticorps Munc30, anticorps Pitx2a, anticorps Pitx2b, anticorps Pitx2c, anticorps Pitx2cbeta, anticorps Ptx2, anticorps Rieg, anticorps pitx2a, anticorps pitx2c, anticorps zgc:110508, anticorps XPtx2b, anticorps xPtx2, anticorps xpitx2, anticorps arp1, anticorps brx1, anticorps idg2, anticorps igds, anticorps igds2, anticorps ihg2, anticorps irid2, anticorps otlx2, anticorps pitx2-A, anticorps ptx2, anticorps rgs, anticorps rieg, anticorps rieg1, anticorps pitx-2, anticorps pitx2, anticorps paired like homeodomain 2, anticorps paired-like homeodomain transcription factor 2, anticorps paired-like homeodomain 2, anticorps paired like homeodomain 2 S homeolog, anticorps paired like homeodomain 2 L homeolog, anticorps PITX2, anticorps Pitx2, anticorps pitx2, anticorps pitx2.S, anticorps pitx2.L

Sujet: Pilx2 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. It plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this protein are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development.

UniProt: Q99697

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development