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PUMA anticorps (AA 119-154)

BBC3 Reactivité: Humain WB, ELISA, IHC, FACS, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3030112
  • Antigène Voir toutes PUMA (BBC3) Anticorps
    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
    Épitope
    • 16
    • 13
    • 9
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 119-154
    Reactivité
    • 91
    • 40
    • 38
    • 16
    Humain
    Hôte
    • 88
    • 6
    • 1
    Lapin
    Clonalité
    • 80
    • 15
    Polyclonal
    Conjugué
    • 47
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PUMA est non-conjugé
    Application
    • 76
    • 33
    • 28
    • 20
    • 16
    • 14
    • 13
    • 11
    • 9
    • 7
    • 5
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
    Réactivité croisée (Details)
    Expected species reactivity: Mouse, Rat
    Purification
    Purified
    Immunogène
    A portion of amino acids 119-154 (BH3 domain) from the human protein was used as the immunogen for this Puma antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product BBC3 Anticorps primaire
  • Indications d'application
    Titration of the Puma antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot the Puma antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Antigène
    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
    Autre désignation
    Puma (BBC3 Produits)
    Synonymes
    anticorps BBC3, anticorps Puma, anticorps JFY-1, anticorps JFY1, anticorps PUMA, anticorps PUMA/JFY1, anticorps BCL2 binding component 3, anticorps Bcl-2 binding component 3, anticorps BBC3, anticorps Bbc3, anticorps bbc3
    Sujet
    PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.
    UniProt
    Q9BXH1
    Pathways
    Signalisation p53, Positive Regulation of Endopeptidase Activity
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