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Retinoblastoma Protein (Rb) anticorps (AA 586-615)

Rb Protein Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3032465
  • Antigène Voir toutes Retinoblastoma Protein (Rb) (Rb Protein) Anticorps
    Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
    Épitope
    • 16
    • 15
    • 14
    • 14
    • 14
    • 10
    • 9
    • 9
    • 8
    • 7
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 586-615
    Reactivité
    • 179
    • 75
    • 60
    • 8
    • 8
    • 7
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 155
    • 25
    Lapin
    Clonalité
    • 153
    • 27
    Polyclonal
    Conjugué
    • 90
    • 17
    • 10
    • 9
    • 9
    • 9
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    Cet anticorp Retinoblastoma Protein (Rb) est non-conjugé
    Application
    • 92
    • 92
    • 85
    • 28
    • 26
    • 16
    • 13
    • 9
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purification
    Antigen affinity purified
    Immunogène
    A portion of amino acids 586-615 from the human protein was used as the immunogen for this Rb antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product Rb Protein Anticorps primaire
  • Indications d'application
    Titration of the Rb antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot the Rb antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Antigène
    Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
    Autre désignation
    Rb (Retinoblastoma) (Rb Protein Produits)
    Sujet
    The retinoblastoma protein is a tumor suppressor protein that is dysfunctional in many types of cancer. One highly studied function of pRb is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide. pRb belongs to the pocket protein family, whose members have a pocket for the functional binding of other proteins. Should an oncogenic protein, such as those produced by cells infected by high-risk types of human papillomaviruses, bind and inactivate pRb, this can lead to cancer. Retinoblastoma (Rb) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral.
    UniProt
    P06400
    Pathways
    Mitotic G1-G1/S Phases
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