Retinoblastoma Protein (Rb) anticorps (AA 858-886)
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- Antigène Voir toutes Retinoblastoma Protein (Rb) (Rb Protein) Anticorps
- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
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Épitope
- AA 858-886
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Retinoblastoma Protein (Rb) est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Réactivité croisée (Details)
- Expected species reactivity: Rat
- Purification
- Purified
- Immunogène
- A portion of amino acids 858-886 from the human protein was used as the immunogen for this Retinoblastoma antibody.
- Isotype
- Ig Fraction
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- Indications d'application
- Titration of the Retinoblastoma antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot the Retinoblastoma antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Antigène
- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
- Autre désignation
- Retinoblastoma (Rb Protein Produits)
- Sujet
- RB1/Retinoblastoma is a negative regulator of the cell cycle and was the first tumor suppressor gene found. This protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1.
- UniProt
- P06400
- Pathways
- Mitotic G1-G1/S Phases
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