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SMAD4 anticorps (AA 400-428)

SMAD4 Reactivité: Humain WB, ELISA, IHC, IF, FACS Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3032608
  • Antigène Voir toutes SMAD4 Anticorps
    SMAD4 (SMAD Family Member 4 (SMAD4))
    Épitope
    • 12
    • 11
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 400-428
    Reactivité
    • 86
    • 39
    • 35
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 75
    • 11
    • 1
    Lapin
    Clonalité
    • 61
    • 26
    Polyclonal
    Conjugué
    • 53
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SMAD4 est non-conjugé
    Application
    • 60
    • 35
    • 31
    • 23
    • 20
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
    Réactivité croisée (Details)
    Expected species reactivity: Mouse, Rat, Bovine, Pig
    Purification
    Purified
    Immunogène
    A portion of amino acids 400-428 from the human protein was used as the immunogen for this SMAD4 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SMAD4 Anticorps primaire
  • Indications d'application
    Titration of the SMAD4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot the SMAD4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Antigène
    SMAD4 (SMAD Family Member 4 (SMAD4))
    Autre désignation
    SMAD4 (SMAD4 Produits)
    Sujet
    In muscle physiology, SMAD4 plays a central role in the balance between atrophy and hypertrophy. When recruited by MSTN, promotes atrophy response via phosphorylated SMAD2/4. MSTN decrease causes SMAD4 release and subsequent recruitment by the BMP pathway to promote hypertrophy via phosphorylated SMAD1/5/8. Acts synergistically with SMAD1 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to SMAD binding elements (SBEs) (5'-GTCT/AGAC-3') within BMP response element (BMPRE) of cardiac activating regions (By similarity). [UniProt]
    UniProt
    Q13485
    Pathways
    Cycle Cellulaire, Chromatin Binding, Autophagy
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