SP1 anticorps

N° du produit ABIN3032703

Détail du produit anti-SP1 anticorps

Antigène: SP1 (Sp1 Transcription Factor (SP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Purification: Purified

Immunogène: This SP1 antibody was produced from a mouse immunized with recombinant Specificity Protein 1.

Clone: 1326CT463-109-176

Isotype: IgG1 kappa

Information d'application

Indications d'application: Titration of the SP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Flow Cytometry: 1:25,Immunofluorescence: 1:25,Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the SP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur SP1

Antigène: SP1 (Sp1 Transcription Factor (SP1))

Autre désignation: SP1 (SP1 Produits)

Synonymes: anticorps fc18h09, anticorps zgc:85950, anticorps wu:fc18h09, anticorps SP1, anticorps 1110003E12Rik, anticorps AA450830, anticorps AI845540, anticorps Sp1-1, anticorps sp1 transcription factor, anticorps Sp1 transcription factor, anticorps Sp1 transcription factor L homeolog, anticorps trans-acting transcription factor 1, anticorps sp1, anticorps SP1, anticorps Sp1, anticorps sp1.L

Sujet: Specificity Protein 1/SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR- alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. In complex with ATF7IP, maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression. [UniProt]

UniProt: P08047

Pathways: Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction