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SPHK1 anticorps (AA 313-343)

SPHK1 Reactivité: Humain WB, IHC, ELISA, FACS Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3032708
  • Antigène Voir toutes SPHK1 Anticorps
    SPHK1 (Sphingosine Kinase 1 (SPHK1))
    Épitope
    • 15
    • 9
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 313-343
    Reactivité
    • 101
    • 48
    • 43
    • 9
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 92
    • 9
    • 1
    Lapin
    Clonalité
    • 88
    • 14
    Polyclonal
    Conjugué
    • 51
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SPHK1 est non-conjugé
    Application
    • 69
    • 40
    • 23
    • 18
    • 13
    • 13
    • 12
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
    Purification
    Purified
    Immunogène
    A portion of amino acids 313-343 from the human protein was used as the immunogen for this SPHK1 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SPHK1 Anticorps primaire
  • Indications d'application
    Titration of the SPHK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot the SPHK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Antigène
    SPHK1 (Sphingosine Kinase 1 (SPHK1))
    Autre désignation
    SPHK1 (SPHK1 Produits)
    Synonymes
    anticorps CG1747, anticorps Dmel\\CG1747, anticorps SK1, anticorps Sphk1, anticorps SPHK1, anticorps F18E5.160, anticorps F18E5_160, anticorps sphingosine kinase 1, anticorps SPHK, anticorps 1110006G24Rik, anticorps Sk1, anticorps Spk1, anticorps Sphingosine kinase 1, anticorps sphingosine kinase 1, anticorps sphingosine kinase 1 L homeolog, anticorps Sk1, anticorps SPHK1, anticorps sphk1.L, anticorps Sphk1
    Sujet
    SPHK1 is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.
    UniProt
    Q9NYA1
    Pathways
    VEGF Signaling
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