SUMO2/3 anticorps (AA 49-81)

N° du produit ABIN3032650

Détail du produit anti-SUMO2/3 anticorps

Antigène: SUMO2/3 (Small Ubiquitin Related Modifier 2/3 (SUMO2/3))

Épitope: AA 49-81

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUMO2/3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (IHC)

Réactivité croisée (Details): Expected species reactivity: Bovine, Chicken, Hamster, Pig, Primate, Rat, Xenopus, Zebrafish

Purification: Purified

Immunogène: A portion of amino acids 49-81 from human SUMO3 was used as the immunogen for this SUMO2/3 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the SUMO2/3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:25-100,Western blot: 1:1000,IHC (FFPE): 1:50-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the SUMO2/3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur SUMO2/3

Antigène: SUMO2/3 (Small Ubiquitin Related Modifier 2/3 (SUMO2/3))

Autre désignation: SUMO2/3 (SUMO2/3 Produits)

Synonymes: anticorps SUMO2, anticorps small ubiquitin-like modifier 2, anticorps SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)-like, anticorps small ubiquitin-related modifier 2, anticorps SUMO2, anticorps LOC711990, anticorps LOC714892

Sujet: SUMO2 and SUMO3 are members of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.

UniProt: P55854