TLR9 anticorps (AA 842-870)

N° du produit ABIN3029183

Détail du produit anti-TLR9 anticorps

Antigène: TLR9 (Toll-Like Receptor 9 (TLR9))

Épitope: AA 842-870

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR9 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 842-870 from the human protein was used as the immunogen for this TLR9 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the TLR9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the TLR9 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur TLR9

Antigène: TLR9 (Toll-Like Receptor 9 (TLR9))

Autre désignation: TLR9 (TLR9 Produits)

Synonymes: anticorps CD289, anticorps toll like receptor 9, anticorps toll-like receptor 9, anticorps TLR9, anticorps Tlr9

Sujet: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.

UniProt: Q9NR96

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades