UBE2I anticorps (AA 1-30)

N° du produit ABIN3029438

Détail du produit anti-UBE2I anticorps

Antigène: UBE2I (Ubiquitin-Conjugating Enzyme E2I (UBE2I))

Épitope: AA 1-30

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2I est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée (Details): Expected species reactivity: Mouse, Rat, Chicken, Zebrafish, Xenopus

Purification: Purified

Immunogène: A portion of amino acids 1-30 from the human protein was used as the immunogen for this UBC9 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the UBC9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the UBC9 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur UBE2I

Antigène: UBE2I (Ubiquitin-Conjugating Enzyme E2I (UBE2I))

Autre désignation: UBC9 (UBE2I Produits)

Synonymes: anticorps C358B7.1, anticorps P18, anticorps UBC9, anticorps ubc9, anticorps ube2ia, anticorps zUbc9, anticorps 5830467E05Rik, anticorps F830028O17Rik, anticorps Ubce2i, anticorps Ubce9, anticorps UbcE2A, anticorps ubce9, anticorps T13J8.70, anticorps T13J8_70, anticorps UBIQUITIN-PROTEIN LIGASE, anticorps ubiquitin conjugating enzyme 9, anticorps ubiquitin conjugating enzyme E2 I, anticorps ubiquitin-conjugating enzyme E2Ib, anticorps ubiquitin-conjugating enzyme E2L, anticorps ubiquitin-conjugating enzyme E2I, anticorps ubiquitin conjugating enzyme E2I S homeolog, anticorps ubiquitin conjugating enzyme 9, anticorps SUMO-conjugating enzyme UBC9, anticorps UBE2I, anticorps ube2ib, anticorps UBE2L, anticorps Ube2i, anticorps ube2i.S, anticorps UBC9, anticorps ubc-9, anticorps LOC108703134

Sujet: UBE2I (Ubc9) is a member of the E2 family and is specific for the conjugation of SUMO to a variety of target proteins. SUMO conjugation to target proteins is mediated by a different, but analogous, pathway to ubiquitinylation. This E2 is unusual in that it interacts directly with protein substrates that are modified by sumoylation, and may play a role in substrate recognition. UBE2I can mediate the conjugation of SUMO-1 to a variety of proteins including RanGAP1, I?B?, and PML without the requirement of an E3 ligase. UBE2I is essential for nuclear architecture and chromosome segregation.

UniProt: P63279

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Ubiquitin Proteasome Pathway