Calprotectin anticorps

N° du produit ABIN4956353

Détail du produit anti-Calprotectin anticorps

Antigène: Calprotectin (S100A8/A9)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Calprotectin est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Réactivité croisée: Humain

Purification: purified

Immunogène: human recombinant protein

Clone: 69-6-1

Isotype: IgG2b

Information d'application

Indications d'application: Dilution: WB 1:1000

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with 1 mL deionized water

Buffer: PBS, pH 7.23

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Détails sur Calprotectin

Antigène: Calprotectin (S100A8/A9)

Autre désignation: calprotectin- S100A8/A9 complex (S100A8/A9 Produits)

Synonymes: anticorps 60B8AG, anticorps CAGB, anticorps CFAG, anticorps CGLB, anticorps L1AG, anticorps LIAG, anticorps MAC387, anticorps MIF, anticorps MRP14, anticorps NIF, anticorps P14, anticorps Mrp14, anticorps MRP-14, anticorps p14, anticorps 60B8Ag, anticorps AW546964, anticorps BEE22, anticorps Cagb, anticorps GAGB, anticorps L1Ag, anticorps S100 calcium binding protein A9, anticorps S100 calcium binding protein A9 (calgranulin B), anticorps S100A9, anticorps S100a9

Sujet: Calprotectin is a functional heterocomplex of small EF hand calcium-binding proteins S100A8 and S100A9. The heterocomplex is expressed in various cells and tissues and induced upon inflammation. The complex is released by neutrophilic granulocytes in inflammatory disorders such as inflammatory bowel disease and rheumatoid arthritis. Released Calprotectin serves as a leukocyte chemoattractant and modulates inflammation via damage receptors. Via it's binding to the receptor of advanced glycation end-products (RAGE), calprotectin is implicated in chronic inflammatory conditions.

Poids moléculaire: 45 kDa

Pathways: S100 Proteins