CPT2 anticorps (Internal Region)
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- Antigène Voir toutes CPT2 Anticorps
- CPT2 (Carnitine Palmitoyltransferase 2 (CPT2))
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Épitope
- AA 141-154, Internal Region
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Porc, Chien
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CPT2 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Séquence
- C-PKSEYNDQLT RATN
- Specificité
- Recognizes Carnitine O-palmitoyltransferase CPT2
- Réactivité croisée (Details)
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Species reactivity (expected):Rat, Canine (Dog), Bovine, Pig.
Species reactivity (tested):Human, Mouse. - Purification
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
- Immunogène
- Peptide from the internal region of Human CPT2 according to NP_000089.1. Genename: CPT2
- Top Product
- Discover our top product CPT2 Anticorps primaire
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- Indications d'application
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Peptide ELISA: Detection Limit: 1/8000. Western blot: 1-3 μg/mL. Detects a band of Approx 70 kDa in Human and Mouse Liver lysates. An additional band of unknown identity was also consistently observed at 20 kDa. Thisband was successfully blocked by incubation with the immunizing peptide.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- CPT2 (Carnitine Palmitoyltransferase 2 (CPT2))
- Autre désignation
- CPT2 (CPT2 Produits)
- Synonymes
- anticorps CPT1, anticorps CPTASE, anticorps IIAE4, anticorps AI323697, anticorps CPTII, anticorps cg2107, anticorps wu:fa03e08, anticorps wu:fb54a02, anticorps zgc:101627, anticorps carnitine palmitoyltransferase 2, anticorps carnitine O-palmitoyltransferase 2, mitochondrial, anticorps carnitine palmitoyltransferase 2 S homeolog, anticorps CPT2, anticorps LOC100214547, anticorps Cpt2, anticorps cpt2.S, anticorps cpt2
- Sujet
- Carnitine palmitoyltransferase II (CPT2) together with carnitine palmitoyltransferase I oxidizes long-chain fatty acids in the mitochondria. Defects in CPT2 are the cause of carnitine palmitoyltransferase 2 deficiency (CPT2D) also known as CPT-II deficiency or CPT2 deficiency. CPT2D is an autosomal recessive disorder characterized by recurrent myoglobinuria, episodes of muscle pain, stiffness, and rhabdomyolysis. These symptoms are triggered by prolonged exercise, fasting or viral infection and patients are usually young adults. In addition to this classical, late-onset, muscular type, a hepatic or hepatocardiomuscular form has been reported in infants. Clinical pictures in these children or neonates include hypoketotic hypoglycemia, liver dysfunction, cardiomyopathy and sudden death.Synonyms: CPT II, Carnitine O-palmitoyltransferase 2, Carnitine palmitoyltransferase II, mitochondrial
- ID gène
- 1376
- NCBI Accession
- NP_000089
- UniProt
- P23786
- Pathways
- Regulation of Lipid Metabolism by PPARalpha, Monocarboxylic Acid Catabolic Process
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