MYB anticorps (Internal Region)
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- Antigène Voir toutes MYB Anticorps
- MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
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Épitope
- AA 557-569, Internal Region
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Porc
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MYB est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Séquence
- C-HRDQTVKTQK ENT
- Specificité
- This antibody is expected to recognize all reported isofoms (NP_001123645.1, NP_005366.2, NP_001123644.1, NP_001155128.1, NP_001155129.1, NP_001155130.1, NP_001155131.1, NP_001155132.1).
- Réactivité croisée (Details)
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Species reactivity (expected):Mouse, Rat, Canine (Dog), Bovine, Pig.
Species reactivity (tested):Human. - Purification
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
- Immunogène
- Peptide corresponding to internal region of Human c-Myb Genename: MYB
- Top Product
- Discover our top product MYB Anticorps primaire
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- Indications d'application
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Peptide ELISA: Detection Limit: 1/8000. Western blot: 0.5-1.5 μg/mL. Detects a band of Approx 85 kDa in lysates of cell line Jurkat.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
- Autre désignation
- MYB (MYB Produits)
- Synonymes
- anticorps Cmyb, anticorps c-myb, anticorps c-myb_CDS, anticorps efg, anticorps AI550390, anticorps M16449, anticorps cmyb, anticorps xmyb, anticorps MYB proto-oncogene, transcription factor, anticorps myeloblastosis oncogene, anticorps MYB proto-oncogene, transcription factor S homeolog, anticorps v-myb avian myeloblastosis viral oncogene homolog, anticorps MYB, anticorps Myb, anticorps myb.S, anticorps myb
- Sujet
- Myb is a transcriptional activator, DNA-binding protein that recognizes the sequence 5'-YAAC[GT]G-3'. It participates in the control of proliferation and differentiation of hematopoietic progenitor cells. Myb is a transcription factor related to Myc, and is expressed predominantly in haematopoietic cells and immature gastroepithelial cells. TRAF7 stimulates the sumoylation of Myb at Lys-523 and Lys-499, which are the same sites as those used for PIASy-induced sumoylation. A correlation has been established between reduction in sumoylation of Myb and increase in transcriptional activation. Negative influence on transactivation properties by the negative regulatory domain region of c-Myb depends on upon sumoylation.Synonyms: Proto-oncogene c-Myb, Transcriptional activator Myb, c-Myb
- ID gène
- 4602
- NCBI Accession
- NP_005366
- UniProt
- P10242
- Pathways
- Chromatin Binding, Positive Regulation of Immune Effector Process
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