ARR3 anticorps
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- Antigène Voir toutes ARR3 Anticorps
- ARR3 (Arrestin 3, Retinal (X-Arrestin) (ARR3))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ARR3 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody detects endogenous levels of Arrestin-C protein. (region surrounding Glu374)
- Réactivité croisée (Details)
- Species reactivity (tested):Human.
- Purification
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product ARR3 Anticorps primaire
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- Indications d'application
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Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- ARR3 (Arrestin 3, Retinal (X-Arrestin) (ARR3))
- Autre désignation
- Arrestin C / ARR3 (ARR3 Produits)
- Synonymes
- anticorps ARRX, anticorps arr3, anticorps si:bz46j2.6, anticorps zgc:73331, anticorps Arr4, anticorps Car, anticorps Carfl, anticorps Carr, anticorps arr3l, anticorps c-arrestin, anticorps zgc:92697, anticorps arrestin 3, anticorps arrestin 3, retinal (X-arrestin) L homeolog, anticorps arrestin 3, retinal (X-arrestin), anticorps arrestin 3b, retinal (X-arrestin), anticorps arrestin 3, retinal, anticorps arrestin 3a, retinal (X-arrestin), anticorps ARR3, anticorps arr3.L, anticorps arr3, anticorps arr3b, anticorps Arr3, anticorps arr3a
- Sujet
- Members of Arrestin/beta-Arrestin protein family are thought to participate in agonist-mediated desensitization of G protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters or sensory signals. Arrestin-C, also known as retinal cone Arrestin-3, X-Arrestin or cArr, is a member of the Arrestin family of proteins. It is predominantly found in the retina and pineal gland and localizes to the inner and outer segments of red-, green- and blue-cone photoreceptors and the inner plexiform regions. Two Arrestin-C isoforms exist due to alternative splicing. Isoform 1 is the mature full length protein and isoform 2 is truncated, ending with an arginine for amino acid residue 359. Arrestin-C expression is stimulated by retinoic acid. It may play a role in retina-specific signal transduction and bind to photoactivated-phosphorylated red/green opsins. In addition, Arrestin-C forms homodimers and oligomers with beta-Arrestins and may regulate beta-Arrestin mediated signaling.Synonyms: ARRX, C-ARR, C-Arrestin, CAR, Cone arrestin, Retinal cone arrestin-3, X-arrestin
- Poids moléculaire
- approx. 40 kDa
- ID gène
- 407
- NCBI Accession
- NP_004303
- UniProt
- P36575
- Pathways
- Phototransduction, Thromboxane A2 Receptor Signaling
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