Peroxiredoxin 3 anticorps

N° du produit ABIN498491

Détail du produit anti-Peroxiredoxin 3 anticorps

Antigène: Peroxiredoxin 3 (PRDX3)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Peroxiredoxin 3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of PRX III protein. (region surrounding Lys93)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Peroxiredoxin 3

Antigène: Peroxiredoxin 3 (PRDX3)

Autre désignation: Peroxiredoxin-3 / PRDX3 (PRDX3 Produits)

Synonymes: anticorps cb718, anticorps wu:fk49e09, anticorps zgc:110282, anticorps zgc:112512, anticorps MGC83969, anticorps PRDX3, anticorps AOP-1, anticorps AOP1, anticorps HBC189, anticorps MER5, anticorps PRO1748, anticorps SP-22, anticorps prx-III, anticorps AW822249, anticorps Aop1, anticorps D0Tohi1, anticorps Ef2l, anticorps Mer5, anticorps Prx3, anticorps SP22, anticorps TDXM, anticorps MTAP, anticorps peroxiredoxin 3, anticorps peroxiredoxin 3 S homeolog, anticorps peroxiredoxin PRX3, anticorps prdx3, anticorps PRDX3, anticorps prdx3.S, anticorps PRX3, anticorps Prdx3

Sujet: The peroxiredoxin (PRX) family comprises six antioxidant proteins, PRX I, II, III, IV, V and VI, which protect cells from reactive oxygen species (ROS) by preventing the metalcatalyzed oxidation of enzymes. The PRX proteins primarily utilize thioredoxin as the electron donor for antioxidation, although they are fairly promiscuous with regard to the hydroperoxide substrate. In addition to protection from ROS, peroxiredoxins are also involved in cell proliferation, differentiation and gene expression. PRX I, II, IV and VI show diffuse cytoplasmic localization, while PRX III and V exhibit distinct mitochondrial localization. The human PRX I gene encodes a protein that is expressed in several tissues, including liver, kidney, testis, lung and nervous system. PRX II is expressed in testis, while PRX III shows expression in lung. PRX I, II and III are overexpressed in breast cancer and may be involved in its development or progression. Upregulated protein levels of PRX I and II in Alzheimer's disease (AD) and Down syndrome (DS) indicate the involvement of PRX I and II in their pathogenesis.Synonyms: AOP-1, AOP1, Antioxidant protein 1, HBC189, PRDX-3, PRX-III, Protein MER5 homolog, Prx-3, Prx3, Thioredoxin-dependent peroxide reductase mitochondrial

Poids moléculaire: approx. 22 kDa

ID gène: 10935

NCBI Accession: NP_006784

UniProt: P30048

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process